Notes:

Margaret of Anjou (French: Marguerite; 23 March 1430 – 25 August 1482) was the wife of King Henry VI of England. As such, she was Queen of England from 1445 to 1461 and again from 1470 to 1471. Born in the Duchy of Lorraine, into the House of Valois-Anjou, Margaret was the second eldest daughter of René I of Naples and Isabella, Duchess of Lorraine.

She was one of the principal figures in the series of dynastic civil wars known as the Wars of the Roses and at times personally led the Lancastrian faction. Due to her husband's frequent bouts of insanity, Margaret ruled the kingdom in his place. It was she who called for a Great Council in May 1455 that excluded the Yorkist faction headed by Richard, Duke of York, and thus provided the spark that ignited a civil conflict that lasted for over thirty years, decimated the old nobility of England, and caused the deaths of thousands of men, including her only son Edward of Westminster, Prince of Wales, at the Battle of Tewkesbury in 1471.

Margaret was taken prisoner by the victorious Yorkists after the Lancastrian defeat at Tewkesbury. In 1475, she was ransomed by her cousin, King Louis XI of France. She went to live in France as a poor relation of the French king, and she died there at the age of 52.

see https://en.wikipedia.org/wiki/Margaret_of_Anjou

Margaret married King Henry Lancaster, King Henry VI on 23 Apr 1445 in Titchfield Abbey. Henry (son of King Henry Lancaster, - King Henry V and Catherine de Valois) was born on 6 Dec 1421 in Windsor Castle, Berkshire, England; died on 21 May 1471 in Tower of London, London, England; was buried in Windsor Castle, Berkshire, England. [Group Sheet] [Family Chart]

Notes:

Edward of Westminster (13 October 1453 – 4 May 1471), also known as Edward of Lancaster, was the only son of King Henry VI of England and Margaret of Anjou. He was killed at the Battle of Tewkesbury, making him the only heir apparent to the English throne ever to die in battle.

Edward was born at the Palace of Westminster, London, the only son of King Henry VI of England and his wife, Margaret of Anjou. At the time, there was strife between Henry's supporters, and Richard Plantagenet, 3rd Duke of York, who had a claim to the throne and challenged the authority of Henry's officers of state. Henry was suffering from mental illness, and there were widespread rumours that the prince was the result of an affair between his mother and one of her loyal supporters. Edmund Beaufort, 2nd Duke of Somerset and James Butler, 5th Earl of Ormonde, were both suspected of fathering Prince Edward,[1] however, there is no firm evidence to support the rumours, and Henry himself never doubted the boy's legitimacy and publicly acknowledged paternity. Edward was invested as Prince of Wales at Windsor Castle in 1454.

see https://en.wikipedia.org/wiki/Edward_of_Westminster,_Prince_of_Wales

Family/Spouse: Anne Neville. [Group Sheet] [Family Chart]